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Alkylation and dehydrogenation of piperazino[1,2-α]indole derivatives

✍ Scribed by V. I. Shvedov; L. B. Altukhova; V. V. Alekseev; A. N. Grinev


Book ID
112343414
Publisher
Springer US
Year
1970
Tongue
English
Weight
69 KB
Volume
6
Category
Article
ISSN
0009-3122

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Palladium-catalyzed double allylic alkyl
✍ Sébastien Laliberté; Peter K. Dornan; Austin Chen 📂 Article 📅 2010 🏛 Elsevier Science 🌐 French ⚖ 408 KB

The synthesis of pyrazino[1,2-a]indoles via a palladium-catalyzed double allylic alkylation of indole-2hydroxamates is described. The reaction conditions are very mild and allow for a wide variety of substitutions on the indole core.