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Alkylating Agents Derived from Indole. IV. Synthesis of the 5-Nitrogen Mustard of Indole-3-carboxylic Acid 1a

✍ Scribed by DeGraw, Joseph; Goodman, Leon


Book ID
121829916
Publisher
American Chemical Society
Year
1964
Tongue
English
Weight
404 KB
Volume
7
Category
Article
ISSN
0022-2623

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Synthesis of 5-substituted indole deriva
✍ BΓ©la Pete; LΓ‘szlΓ³ TΕ‘ke πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 71 KB

Valuable new synthetic intermediates, 5-chloromethyl-1H-indole-2-carboxylates, were prepared by the elimination of SO 2 from 2-ethoxycarbonyl-1H-indole-5-methanesulfonic acids, which are easily accessible by Fischer-type indolization.