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Alkaloids of Vinca rosea L. (Catharanthus roseus G. Don) XXXVI: Isolation and Characterization of New Dimeric Alkaloids

โœ Scribed by S. Tafur; W. E. Jones; D. E. Dorman; E. E. Logsdon; G. H. Svoboda

Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
500 KB
Volume
64
Category
Article
ISSN
0022-3549

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๐Ÿ“œ SIMILAR VOLUMES

Alkaloids of Vinca rosea Linn. (Catharan
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โœ Gordon H. Svoboda; Marvin Gorman; Norbert Neuss; Albert J. Barnes Jr. ๐Ÿ“‚ Article ๐Ÿ“… 1961 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 451 KB

Continuation of the phytochemical examination of this plant (1) which has produced two antitumor principles, vincaleukoblastine and leurosine, has yielded six previously unreported minor alkaloids in addition to those already reported from these laboratories (2). Details of the procedure leading to

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The unique biological properties of leurosine (2), leurosidine (3), leurocristine (3) and vincaleukoblastine (4), dimeric indole-indoline alkaloids from Vinca rosea Linn. (Catharanthus roseus G. Don) have been -thoroughly reviewed (5). Two of these compound, leurocristine and vincaleukoblastine" hav

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rate of excretion of the metabolite, carboxytolbutamide, in the urine. Indirectly, they show that available surface area of tolbutamide in the dosage form can influence the rate and extent of absorption of tolbutamide if the surface area is restricted in the range studied.