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Vinca alkaloids. XXIX. Structure of leurosidine (vinrosidine, VRD), an oncolytic alkaloid from vinca rosea linn. (catharanthus roseus G. Don)

โœ Scribed by Norbert Neuss; Lyell L. Huckstep; Nancy J. Cone


Publisher
Elsevier Science
Year
1967
Tongue
French
Weight
261 KB
Volume
8
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


The unique biological properties of leurosine (2), leurosidine (3), leurocristine (3) and vincaleukoblastine (4), dimeric indole-indoline alkaloids from Vinca rosea Linn. (Catharanthus roseus G. Don) have been -thoroughly reviewed (5). Two of these compound, leurocristine and vincaleukoblastine" have been introduced as therapeutically useful agents for the treatment of various human neoplasms.


๐Ÿ“œ SIMILAR VOLUMES


Alkaloids of Vinca rosea Linn. (Catharan
โœ Gordon H. Svoboda; Marvin Gorman; Norbert Neuss; Albert J. Barnes Jr. ๐Ÿ“‚ Article ๐Ÿ“… 1961 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 451 KB

Continuation of the phytochemical examination of this plant (1) which has produced two antitumor principles, vincaleukoblastine and leurosine, has yielded six previously unreported minor alkaloids in addition to those already reported from these laboratories (2). Details of the procedure leading to