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Alkaloids from Hippeastrum morelianum Lem. (Amaryllidaceae)

✍ Scribed by Raquel B. Giordani; Jean P. de Andrade; Hugo Verli; Julie H. Dutilh; Amélia T. Henriques; Strahil Berkov; Jaume Bastida; José Angelo S. Zuanazzi

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
126 KB
Volume
49
Category
Article
ISSN
0749-1581

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✦ Synopsis

Abstract

The Amaryllidaceae family has proven to be a rich source of active molecules. As part of an ongoing project, we report a phytochemical study of Hippeastrum morelianum (Amaryllidaceae), from which we have isolated two homolycorine‐type alkaloids, the new 2α,7‐dimethoxyhomolycorine (1) and the poorly described candimine (2), as well as six known alkaloids: tazettine, pretazettine, 3‐epimacronine, haemanthamine, hamayne and trisphaeridine. For reference purposes, the NMR of the isolated compounds was unequivocally described, based on 2D NMR measurements including ^1^H–^1^H COSY, ^1^H–^1^H NOESY, HSQC and HMBC. Copyright © 2011 John Wiley & Sons, Ltd.

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