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Alkaloid Studies. XII. 1 Synthesis of Substituted 1-Isobutyl-2-methyl-1,2,3,4-tetrahydroisoquinolines 2

โœ Scribed by DJERASSI, CARL.; MARKLEY, F. X.; EHRLICH, R.


Book ID
125901296
Publisher
American Chemical Society
Year
1956
Tongue
English
Weight
536 KB
Volume
21
Category
Article
ISSN
0022-3263

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New trans/cis tetrahydroisoquinolines. 1
โœ I. D. Kozekov; R. I. Koleva; M. D. Palamareva ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 82 KB

## Abstract The reaction of homophthalic anhydride and __N__โ€(1โ€methylโ€1__H__โ€pyrrolโ€2โ€ylโ€methylidene)โ€benzylamine in boiling benzene afforded as a main product the expected substituted __trans__โ€1,2,3,4โ€tetrahydroisoquinolineโ€4โ€carboxylic acid **5**. The carboxylic group of **5** was transformed i