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Alignment of protein sequences by their profiles

โœ Scribed by Marc A. Marti-Renom; M.S. Madhusudhan; Andrej Sali

Book ID
111752205
Publisher
Cold Spring Harbor Laboratory Press
Year
2004
Tongue
English
Weight
595 KB
Volume
13
Category
Article
ISSN
0961-8368

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Sequence alignment programs such as BLAST and PSI-BLAST are used routinely in pairwise, profile-based, or intermediate-sequencesearch (ISS) methods to detect remote homologies for the purposes of fold assignment and comparative modeling. Yet, the sequence alignment quality of these methods at low se