We consider the problem of aligning of k sequences of length n. The cost function is sum of pairs, and satisfies triangle inequality. Earlier results on finding approximation algorithms for this problem are due to Gusfield (1991) who achieved an approximation ratio of 2 -2/k, and Pevzner (1992) who
โฆ LIBER โฆ
Algorithms for path-constrained sequence alignment
โ Scribed by Pinhas, Tamar; Milo, Nimrod; Kucherov, Gregory; Ziv-Ukelson, Michal
- Book ID
- 121887458
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 326 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1570-8667
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## Proceedings of the Third Annual ACM-SIAM Discrete Algorithms) find optimal scores for all penalty parameters, both for global and local sequence alignment. This paper reviews those techniques Then in the main part of this paper dynamic programming methods are used to compute ensemble alignment,