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Aldose Reductase Catalyzes Reduction of the Lipid Peroxidation Product 4-Oxonon-2-enal

✍ Scribed by Doorn, Jonathan A.; Srivastava, Satish K.; Petersen, Dennis R.

Book ID
126903960
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
99 KB
Volume
16
Category
Article
ISSN
0893-228X

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## Abstract The aim of this work was to synthesize ^13^C internal standards for the quantification of 4‐hydroxy‐2(E)‐nonenal (HNE), a lipid peroxidation product, and of the etheno‐adducts possibly formed by HNE damage to DNA nucleobases. We designed an eight‐step synthesis starting from ethyl 2‐bro