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Alcohol Intoxication Impairs Phosphorylation of S6K1 and S6 in Skeletal Muscle Independently of Ethanol Metabolism

โœ Scribed by Charles H. Lang; Anne M. Pruznak; Nobuko Deshpande; Margaret M. Palopoli; Robert A. Frost; Thomas C. Vary


Book ID
110086781
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
652 KB
Volume
28
Category
Article
ISSN
0145-6008

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## Abstract Endotoxin (i.e., lipopolysaccharide, LPS) impairs skeletal muscle protein synthesis. Although this impairment is not acutely associated with a decreased plasma concentration of total amino acids, LPS may blunt the anabolic response to amino acids. To examine this hypothesis, rats were i