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Alcohol dehydrogenase 3∗1 genotype is associated with hepatocellular carcinoma in alcohol-induced liver cirrhosis

✍ Scribed by F. Stickel; M. Benesova; H.K. Seitz; I. Zuber-Jerger; C. Hellerbrand; M. Frieser; W.H. Caselmann; H.E. Blum; E.G. Hahn; D. Schuppan

Book ID: 117372164
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 170 KB
Volume: 38
Category: Article
ISSN: 0168-8278
DOI: 10.1016/s0168-8278(03)80073-9

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## Abstract Major etiologic factors associated with human hepatocellular carcinomas (HCCs) include infection with hepatitis C (HCV) and hepatitis B virus (HBV), excess alcohol intake and aflatoxin B~1~ exposure. While the G→T __p53__ mutation at codon 249 has been identified as a genetic hallmark o