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Genetic predisposition for alcohol-associated upper aerodigestive tract cancer and hepatocellular carcinoma in heavy drinkers with the alcohol dehydrogenase 3*1 allele

✍ Scribed by Stickel, Felix; Homann, Nils; Benesova, Monika; Jacobs, Andrea; Schuppan, Detlef; Hahn, Eckhart G.; Conradt, Christian; Ludwig, Dieter; Zuber, Ina; Blum, Hubert E.; Seitz, Helmut K.


Book ID
123112006
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
233 KB
Volume
124
Category
Article
ISSN
0016-5085

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Alcohol dehydrogenase 1C*1 allele is a g
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## Abstract Chronic alcohol consumption is associated with an increased risk for upper aerodigestive tract cancer and hepatocellular carcinoma. Increased acetaldehyde production __via__ alcohol dehydrogenase (ADH) has been implicated in the pathogenesis. The allele ADH1C\*1 of ADH1C encodes for an