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Akt versus p53 in a Network of Oncogenes and Tumor Suppressor Genes Regulating Cell Survival and Death

✍ Scribed by Wee, Keng Boon; Aguda, Baltazar D.

Book ID
119920089
Publisher
Biophysical Society
Year
2006
Tongue
English
Weight
245 KB
Volume
91
Category
Article
ISSN
0006-3495

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Loss of heterozygosity at 4 tumor-suppressor gene loci (pS3, apc, mcc and Rb) was investigated using polymerase chain reactions, in 49 esophageal squamous-cell carcinoma specimens from patients who had undergone curative resection. Mutations in the p53 gene within exons 5 to 8 were also examined. LO