AgOTf-Catalyzed Three-Component Reactions of 2-Alkynylbenzaldehydes, Amines, and Diethylphosphite. An Efficient Route to 2,3-Disubstituted-1,2-dihydroisoquinolin-1-ylphosphonates.
β Scribed by Wei Sun; Qiuping Ding; Xiaoyu Sun; Renhua Fan; Jie Wu
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 19 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The presence of PPF is essential for a successful performance of the title reaction.
Library Construction of 1-(1H-Imidazol-1-yl)-1,2-dihydroisoquinolines via Three-Component Reaction of 2-Alkynylbenzaldehyde, Amine, and Imidazole. -A variety of anilines, substituted alkynylbenzaldehydes and imidazoles can be applied. No reaction takes place when a nonaromatic (benzyl) amine is used