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Aging- and Growth-Dependent Modulation of Endothelin-1 Gene Expression in Human Vascular Endothelial Cells

โœ Scribed by Tsutomu Kumazaki; Takashi Fujii; Mieko Kobayashi; Youji Mitsui


Book ID
115601665
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
315 KB
Volume
211
Category
Article
ISSN
0014-4827

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Endothelin-1 (ET-1) is a potent vasoconstrictor peptide synthesized and secreted by vascular endothelial cells. Regulation of ET-1 production occurs at the level of gene transcription. We previously demonstrated a role for arachidonic acid as an intracellular mediator in the regulation of gene expre