## Abstract Aging of mammalian brain is associated with a continuous decrease of the capacity to produce ATP by oxidative phosphorylation. The impairment of mitochondrial function is mainly due to diminished electron transfer by complexes I and IV, whereas inner membrane H^+^ impermeability and F~1
Aging and diabetes: Mitochondrial dysfunction
β Scribed by Brian A. Irving; K. Sreekumaran Nair
- Publisher
- Current Science Inc.
- Year
- 2007
- Tongue
- English
- Weight
- 155 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1534-4827
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## Abstract Several studies have been carried out to evaluate the alterations in mitochondrial functions of diabetic rats. However, some of the results reported are controversial, since experimental conditions, such as aging, and/or strain of animals used were different. The purpose of this study w