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Mitochondrial dysfunction, insulin resistance, and type 2 diabetes mellitus

✍ Scribed by Muhammad A. Abdul-Ghani; Ralph A. DeFronzo


Publisher
Current Science Inc.
Year
2008
Tongue
English
Weight
262 KB
Volume
8
Category
Article
ISSN
1534-4827

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This review discusses the hypothesis that mitochondrial dysfunction plays a role in the pathogenesis of the most common form of diabetes, type II diabetes mellitus. Mitochondrial mutations have been linked to the development of diabetes mellitus as part of several rare syndromes, accounting for appr