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Aggressive behaviour associated with donepezil treatment: a case report

โœ Scribed by Angelo Bianchetti; Marco Trabucchi; Giovanna Cipriani

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
32 KB
Volume
18
Category
Article
ISSN
0885-6230

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โœฆ Synopsis

overt cerebrovascular disease. This clinical features of late age of onset, presence of vascular risk factors, WML on MRI and treatment resistance are typical of 'vascular depression' (O'Brien et al., 1998; Baldwin and O'Brien, 2002). Although we cannot prove causation, we hypothesise that ischaemic damage to FSC underpinned both initial depression and poor outcome. Chronic ischaemia might have been caused by chonic low oxygen saturation because of COAD. This case, with presentation in association with physical health difficulties, is typical of depression in later life. However, we propose there may be biological, as well as psychological, associations underpinning this well documented relationship.

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