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Aggregation properties of semisynthetic GM1 ganglioside (II3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety

✍ Scribed by Sandro Sonnino; Laura Cantu'; Mario Corti; Domenico Acquotti; Gunther Kirschner; Guido Tettamanti

Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 782 KB
Volume: 56
Category: Article
ISSN: 0009-3084
DOI: 10.1016/0009-3084(90)90087-8

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✦ Synopsis

The aggregative properties of GM1 ganglioside containing an acetyl group as acyl moiety [GM1(acetyl)] in aqueous solution have been studied by static and dynamic light scattering measurements and surface tension experiments. GM1 (acetyl) spontaneously aggregates as small micelles showing a hydrodynamic radius and molecular weight of 34 A and 102 kDa, respectively, down to a concentration of 2.0 x 10(-5) M.

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