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Aggregation properties of semisynthetic GD1a ganglioside (IV3Neu5ACII3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety

โœ Scribed by Paola Brocca; Laura Cantu'; Sandro Sonnino


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
697 KB
Volume
77
Category
Article
ISSN
0009-3084

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โœ Sandro Sonnino; Laura Cantu'; Mario Corti; Domenico Acquotti; Gunther Kirschner; ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 782 KB

The aggregative properties of GM1 ganglioside containing an acetyl group as acyl moiety [GM1(acetyl)] in aqueous solution have been studied by static and dynamic light scattering measurements and surface tension experiments. GM1 (acetyl) spontaneously aggregates as small micelles showing a hydrodyna

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GM1 ganglioside containing a hydroxylated fatty acid moiety, GMI(OH), was synthesized starting from lyso-GMl and D-(+)-2-hydroxystearic acid. The aggregative, geometrical and distribution properties of GMI(OH) were compared with those of stearic acid containing GM 1 ganglioside; laser light scatteri