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Age-related changes in learning and memory and cholinergic neuronal function in senescence accelerated mice (SAM)

✍ Scribed by Atsumi Nitta; Kazumasa Naruhashi; Masayuki Umemura; Takaaki Hasegawa; Shoei Furukawa; Fujio Sekiguchi; Kotaro Ishibashi; Toshitaka Nabeshima


Book ID
116104150
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
610 KB
Volume
72
Category
Article
ISSN
0166-4328

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Twelve substrains of inbred senescence-accelerated mice (SAM) have been developed, among which the SAMP8 and SAMP10 strains show a significant age-related deterioration in learning and memory for passive and active avoidance tasks. These strains have, respectively, a low and high incidence of system