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Age-dependent modifications of Type 1 and Type 2 cytokines within virgin and memory CD4+ T cells in humans

โœ Scribed by S. Alberti; E. Cevenini; R. Ostan; M. Capri; S. Salvioli; L. Bucci; L. Ginaldi; M. De Martinis; C. Franceschi; D. Monti


Book ID
113775945
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
296 KB
Volume
127
Category
Article
ISSN
0047-6374

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CD4 + and CD8 + T cells can be divided based on the cytokines that they secrete into type 1 (Th1, Tc1) and type 2 (Th2, Tc2) subsets. Schistosoma mansoni infection in mice is characterized by a type 2-dominated response. We have used intracellular cytokine staining to demonstrate dramatic changes in