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CD4+ T-cell type 1 and type 2 cytokines in the HSV-1 infected cornea

✍ Scribed by A. Heiligenhaus; Dirk Bauer; Mei Zheng; Stefanie Mrzyk; Klaus-Peter Steuhl


Book ID
106099185
Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
320 KB
Volume
237
Category
Article
ISSN
0065-6100

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CD4 + and CD8 + T cells can be divided based on the cytokines that they secrete into type 1 (Th1, Tc1) and type 2 (Th2, Tc2) subsets. Schistosoma mansoni infection in mice is characterized by a type 2-dominated response. We have used intracellular cytokine staining to demonstrate dramatic changes in