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Age-dependent change in activities of lysosomal enzymes in rat brain

✍ Scribed by Yu Nakamura; Masatoshi Takeda; Hideo Suzuki; Hitoshi Morita; Kunitoshi Tada; Shiro Hariguchi; Tsuyoshi Nishimura


Book ID
119026129
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
613 KB
Volume
50
Category
Article
ISSN
0047-6374

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Streptozotocin-induced diabetes resulted in a decrease in the cathepsin D activity (free and total) in rat liver, kidney, brain and heart with a concomitant increase in tissue protein content and amino acids pool size. Treatment with insulin brought about the restoration of the cathepsin D activity