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Age at menopause predicts age at onset of Parkinson's disease

✍ Scribed by Paolo Ragonese; Marco D'Amelio; Graziella Callari; Giuseppe Salemi; Letterio Morgante; Giovanni Savettieri

Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 61 KB
Volume: 21
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.21127

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD. © 2006 Movement Disorder Society

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