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Ag-Catalyzed Diastereo- and Enantioselective Synthesis of β-Substituted Tryptophans from Sulfonylindoles

✍ Scribed by Zheng, Bao-Hui; Ding, Chang-Hua; Hou, Xue-Long; Dai, Li-Xin

Book ID
127257119
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
266 KB
Volume
12
Category
Article
ISSN
1523-7060

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ChemInform Abstract: Highly Diastereo- a
ChemInform Abstract: Highly Diastereo- and Enantioselective Synthesis of syn-β-Substituted Tryptophans via Asymmetric Michael Addition of a Chiral Equivalent of Nucleophilic Glycine and Sulfonylindoles.
✍ Jiang Wang; Shengbin Zhou; Daizong Lin; Xiao Ding; Hualiang Jiang; Hong Liu 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 50 KB 👁 1 views

## Abstract The asymmetric Michael addition of a chiral Ni(II) complex of a Schiff base of glycine (I) with a broad range of sulfonylindoles offers a simple and mild protocol for the preparation of syn‐configured β‐substituted tryptophans.