𝔖 Bobbio Scriptorium
✦   LIBER   ✦

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

✍ Scribed by Burgering, Boudewijn M. T.; Medema, René H.; Kops, Geert J. P. L.; Bos, Johannes L.


Book ID
109768257
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
333 KB
Volume
404
Category
Article
ISSN
0028-0836

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


PKB/Akt mediates cell-cycle progression
✍ Shin, Incheol; Yakes, F Michael; Rojo, Federico; Shin, Nah-Young; Bakin, Andrei 📂 Article 📅 2002 🏛 Nature Publishing Group 🌐 English ⚖ 826 KB

We have shown a novel mechanism of Akt-mediated regulation of the CDK inhibitor p27(kip1). Blockade of HER2/neu in tumor cells inhibits Akt kinase activity and upregulates nuclear levels of the CDK inhibitor (Kip1). Recombinant Akt and Akt precipitated from tumor cells phosphorylated wild-type p27 i

Magnesium deficiency suppresses cell cyc
✍ Akira Ikari; Hayato Sawada; Ayumi Sanada; Chie Tonegawa; Yasuhiro Yamazaki; Junk 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 485 KB 👁 2 views

Lack of magnesium suppresses cell growth, but the molecular mechanism is not examined in detail. We examined the effect of extracellular magnesium deficiency on cell cycle progression and the expression of cell cycle regulators in renal epithelial NRK-52E cells. In synchronized cells caused by serum