Two examples are described of the use of NMR spectroscopy to study the modification of DNA structure by carcinogens. The reaction of ethylene dibromide involves initial conjugation with glutathione, catalysed by glutathione S-transferase. Reaction of this adduct with DNA occurs at N7 of guanine. Thr
โฆ LIBER โฆ
Aflatoxin B1Epoxide, the Ultimate Carcinogenic form of Aflatoxin B1: Synthesis and Reaction with Dna
โ Scribed by Harris, T. M. ;Stone, M. P. ;Gopalakrishnan, S. ;Baertschi, S. W. ;Raney, K. D. ;Byrd, S.
- Book ID
- 125483701
- Publisher
- Taylor and Francis Group
- Year
- 1989
- Tongue
- English
- Weight
- 448 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1525-6057
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