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Affinity of Cu+ for the Copper-Binding Domain of the Amyloid-β Peptide of Alzheimer’s Disease

✍ Scribed by Feaga, Heather A.; Maduka, Richard C.; Foster, Monique N.; Szalai, Veronika A.

Book ID
111923077
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
890 KB
Volume
50
Category
Article
ISSN
0020-1669

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## Abstract Amyloid‐β peptide (Aβ) is the principal constituent of plaques associated with Alzheimer's disease (AD) and is thought to be responsible for the neurotoxicity associated with the disease. Copper binding to Aβ has been hypothesized to play an important role in the neruotoxicity of Aβ and