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Affinity modification of human chromatin with reactive derivatives of oligonucleotides

โœ Scribed by E.L. Chernolovskaya; N.D. Kobets; R.G. Borissov; T.V. Abramova; V.V. Vlassov


Book ID
117980346
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
309 KB
Volume
303
Category
Article
ISSN
0014-5793

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โœ V. V. Vlassov; N. D. Kobetz; E. L. Chernolovskaya; S. G. Demidova; R. G. Borisso ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer ๐ŸŒ English โš– 301 KB

Chemical modification of the chromatin DNA with alkylating derivatives of oligothymidylate (pT)16 and oligoadenylate (pA)16 bearing 4-(N-2-chloroethyl-N-methylamino)benzylphosphamide group at the 5'-phosphate has been investigated. It was found that the derivatives do react with DNA in chromatin. Th