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Affinity Maturation of Human Growth Hormone by Monovalent Phage Display

โœ Scribed by Henry B. Lowman; James A. Wells

Book ID
115626257
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
1004 KB
Volume
234
Category
Article
ISSN
0022-2836

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Peptides derived from almost all proteins, including disease-associated proteins, can be presented on the cell surface as peptide-human leukocyte antigen (pHLA) complexes. T cells specifically recognize pHLA with their clonally rearranged T-cell receptors (TCRs), whose natural affinities are limited