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Aetiology and pathogenesis of thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome: the role of von Willebrand factor-cleaving protease

✍ Scribed by Miha Furlan; Bernhard Lämmle


Book ID
119755008
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
255 KB
Volume
14
Category
Article
ISSN
1521-6926

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## Abstract Decreased von Willebrand factor (VWF)‐cleaving protease activity (<5%) has been implicated in patients with congenital thrombotic thrombocytopenic purpura–hemolytic uremic syndrome (Upshaw‐Schulman syndrome) and associated with mutations within the __ADAMTS13__ gene. In this report, we