Aeruginazole A, a Novel Thiazole-Containing Cyclopeptide from the Cyanobacterium Microcystis sp.
โ Scribed by Raveh, Avi; Carmeli, Shmuel
- Book ID
- 118145381
- Publisher
- American Chemical Society
- Year
- 2010
- Tongue
- English
- Weight
- 209 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1523-7060
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๐ SIMILAR VOLUMES
Micropeptin T-20, a novel glyceric acid 3-O-phosphate and 3-amino-6-hydrooxy-2-piperidonecontaining cyclic depsipeptide, was isolated from a cyanobacterium Microcystis aeruginosa. The structure was identified as 1 by 2D NMR and chemical degradation analyses. Micropeptin T-20 inhibited chymotrypsin.
## a b s t r a c t Two new thiazole-containing cyclic hexapeptides, microcyclamides MZ602 and MZ568, were isolated from the hydrophilic extract of the cyanobacterium Microcystis sp. The structures of the pure natural products were elucidated using spectroscopic methods including UV, 1D and 2D NMR,
Three new protease inhibitors, micropeptins SF909 (1) and SF995 (2) and microcin SF608 (3), were isolated from the hydrophilic extract ofa microcystis sp. waterbloom. The planar structure of compounds !-3 was determined by homonuclear and inverse-heteronuelear 2D-NMR techniques as well as high-resol