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Aerosol gene delivery to the murine lung is mouse strain dependent

✍ Scribed by Petra Dames; Aurora Ortiz; Ulrike Schillinger; Eugenia Lesina; Christian Plank; Joseph Rosenecker; Carsten Rudolph

Book ID
105796497
Publisher
Springer
Year
2006
Tongue
English
Weight
210 KB
Volume
85
Category
Article
ISSN
0946-2716

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A miniaturized nebulization catheter for
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✍ Magnus KΓΆping-HΓΆggΓ₯rd; Mohamed M. Issa; Tamara KΓΆhler; Ann Tronde; Kjell M. VΓ₯ru πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 223 KB

## Abstract ## Background The available methods for administration of gene delivery systems to the lungs of small animals via nebulization have several drawbacks. These include lack of control over the delivered dose and a negative impact on the stability of the formulation. This paper describes a

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Methodological optimization of polyethylenimine (PEI)-based gene delivery to the lungs of mice via aerosol application
✍ C. Rudolph; A. Ortiz; U. Schillinger; J. Jauernig; C. Plank; J. Rosenecker πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 135 KB

## Abstract ## Background Polyethylenimine (PEI) has been successfully used for gene delivery to the lungs of mice via aerosol application using a whole body nebulization device. In this report we optimized the design of such an aerosol device. ## Methods Aerosol devices were constructed as eith