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Dry powder aerosols of polyethylenimine (PEI)-based gene vectors mediate efficient gene delivery to the lung

✍ Scribed by Corinna Pfeifer; Guenther Hasenpusch; Senta Uezguen; Manish Kumar Aneja; Dietrich Reinhardt; Julian Kirch; Marc Schneider; Sarah Claus; Wolfgang Frieß; Carsten Rudolph

Book ID
113694663
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
757 KB
Volume
154
Category
Article
ISSN
0168-3659

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Methodological optimization of polyethyl
Methodological optimization of polyethylenimine (PEI)-based gene delivery to the lungs of mice via aerosol application
✍ C. Rudolph; A. Ortiz; U. Schillinger; J. Jauernig; C. Plank; J. Rosenecker 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 135 KB

## Abstract ## Background Polyethylenimine (PEI) has been successfully used for gene delivery to the lungs of mice via aerosol application using a whole body nebulization device. In this report we optimized the design of such an aerosol device. ## Methods Aerosol devices were constructed as eith