Twenty-four patients with acute promyelocytic leukemia were reviewed. Group I, treated between July 1970 and September 1973, received arabinosylcytosine and 6-thioguanine, and there was one complete remission, with 4 7 dying during induction with intracerebral hemorrhages, and 217 dying within one m
Advances in therapies for acute promyelocytic leukemia
β Scribed by Tomohiko Kamimura; Toshihiro Miyamoto; Mine Harada; Koichi Akashi
- Book ID
- 108589140
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 160 KB
- Volume
- 102
- Category
- Article
- ISSN
- 1347-9032
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π SIMILAR VOLUMES
Acute promyelocytic leukemia (APL) is a subset of acute myeloid leukemia characterized by the morphology of the blast cells (M3 type in the FAB nomenclature), and a specific t(15;17) translocation. APL was further characterized by a specific sensitivity to all-trans retinoic acid's differentiation e
34 patients with acute promyelocytic leukemia (APL) were treated with daunorubicin (DNR) alone and simultaneous supportive therapy with low-dose heparin, platelet transfusions, and fresh frozen plasma. Two consecutive maintenance therapy regimens were employed in patients who achieved complete remis
## Abstract Sixteen children (ages 2β17) with acute promyelocytic leukemia (APL) were studied retrospectively. Diagnosis was based on clinical features and morphological criteria of the FAB classification. Bleeding diathesis was the predominant presenting symptom (>85%), associated with laboratory