Thrombotic and thromboembolic disorders, in particular, thrombosis complicating life style-related diseases such as malignancies and arterioscleosis resulting from diabetes mellitus, hypertension, obesity and others, are now, more than ever, the leading causes of morbidity and mortality and become t
Advances in Hemostasis and Thrombosis
โ Scribed by Angelo Baserga (auth.), A. Cajozzo, R. Perricone, P. Di Marco, P. Palazzolo (eds.)
- Publisher
- Springer US
- Year
- 1985
- Tongue
- English
- Leaves
- 330
- Series
- Ettore Majorana International Science Series 20
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
โฆ Synopsis
A greater knowledge of the basic molecular mechanisms which regulate platelet function, coagulation, the fibrinolytic system and their interaction with the vessel wall has allowed a better understanding of the numerous aspects involved in the pathogenesis of thrombosis and the regulation of hemostasis. Thrombosis represents today one of the causes of death in the Western hemisphere. Arterial thrombosis may lead to myocardial infarction, cerebral and peripheral vascular diseases. Venous thrombosis, on the other hand, is a complication of heart disease, surgery, extensive trauma, several obstetric pathologies, and may, at times, develop in apparently healthy subjects. These complex problems are dealt with within the content of "Advances in Hemostasis and Thrombosis." The present papers contain up-to-date information on hemostasis, the role of prostaglandins, fibrinolytic coagulation, rheology, and modern therapeutic approaches along with their clinical application. This book, therefore, offers the reader the opportunity to profit from a rare encounter, an interdisciplinary cooperation, with scientific contributions from numerous countries.
โฆ Table of Contents
Front Matter....Pages i-x
Hemostasis: A Review....Pages 1-5
Platelets, Endothelium and Vessel Injury....Pages 7-16
Roles of Thrombospondin and Fibronectin in Vascular Injury....Pages 17-26
The Interaction of Fibronectin, Endothelium, and Subendothelium....Pages 27-40
Platelets and the Platelet-Derived Growth Factor in the Pathogenesis of Atherosclerosis....Pages 41-49
Monoclonal Antibodies to Human von Willebrand Factor Study of its Structure-Function Relationship....Pages 51-58
The Membrane Glycoproteins: Adhesion and Aggregation of Platelets....Pages 59-74
The Changes in Arachidonic Acid Metabolism in Ischemic Heart Disease โ Their Pathophysiological Consequences....Pages 75-77
Hemorheology and Thrombosis....Pages 79-91
Blood Cells and Thrombosis: The Rheology and Activation of the Coagulative Process....Pages 93-102
Procoagulant Activity of Platelets, Leukocytes, and Cancer Cells Possible Role in Hemostasis and Thrombosis....Pages 103-115
Antithrombin III and Other Natural Inhibitors of Coagulation....Pages 117-128
On the Evaluation of the Thrombotic Risk....Pages 129-140
The Correlation Between Fatty Acids and Platelet Function....Pages 141-148
Protein C โ An Inhibitor of Blood Coagulation: Biochemistry, Physiology, Clinical Aspects....Pages 149-157
Immune Complexes and Thrombosis....Pages 159-171
Hemostatic Parameters and Ischemic Heart Disease....Pages 173-190
Critical Review of Myocardial Infarction Prevention with Antiaggregants....Pages 191-205
Hemostatic Alterations in Diabetes Mellitus....Pages 207-212
Hemostatic Alterations in Peripheral Arteriopathies....Pages 213-222
Hemostatic Alterations in Cerebrovascular Insufficiency....Pages 223-230
Minor Fibrinolytics and Thrombolytics in Clinic....Pages 231-243
Thrombolytic Properties of Human Tissue-Type Plasminogen Activator....Pages 245-249
The Anticoagulant Properties of Fractionated and Depolymerized Heparins....Pages 251-260
Clinical and Biological Aspects of Essential Thrombocythemia....Pages 261-270
The Fibrinolytic Activity of Malignant Cells....Pages 271-275
Oral Anticoagulants in the Prevention and Treatment of Vascular Disorders....Pages 277-287
Prevention of Postoperative Venous Thromboembolism by a New Low Molecular Weight Heparin Fraction....Pages 289-302
Disseminated Intravascular Coagulation....Pages 303-314
ฮฒ-TG and PF 4 in the Diagnosis of Thrombosis....Pages 315-321
Is Platelet Survival a Predictive Test for Thrombosis?....Pages 323-326
Back Matter....Pages 327-334
โฆ Subjects
Physics, general
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