The cellular origin of H-RS cells has been questioned for a long time. Recently, using single cell amplification of Ig genes evidence was obtained that H-RS cells clonally arise from B-cells. Sequence analysis of rearranged Ig genes demonstrated that H-RS cells develop within the germinal centre. H-
Advances in Biology, Diagnostics, and Treatment of Hodgkin’s Disease
✍ Scribed by Ralf Küppers; Joachim Yahalom; Andreas Josting
- Book ID
- 116278441
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 514 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1083-8791
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