The retinoblastoma susceptibility (RE3) gene is unique among other cloned cancer genes because its causal role in a human cancer, retinoblastoma, was established by classical genetic methods before its isolation. Earlier hypotheses and experimental data suggested that inactivation of a gene in chrom
Advanced studies on human gene ZNF322
โ Scribed by Li, Yongqing ;Wang, Yuequn ;Yuan, Wuzhou ;Deng, Yun ;Zhu, Chuanbing ;Wu, Xiushan
- Book ID
- 107382612
- Publisher
- Higher Education Press and Springer
- Year
- 2007
- Tongue
- English
- Weight
- 351 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1673-3509
No coin nor oath required. For personal study only.
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Gene amplification is a model of proto-oncogene alterations occasionally observed in human tumors. This amplification can, in some cases, have prognostic value (N-myc in neuroblastoma, c-erbB2 and int-2 in breast cancer, etc.). Amplifications of the proto-oncogenes c-myc, c-erbB2 and int-2 have not
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