A 67-year-old woman was admitted to our hospital because of lymphadenopathy and lymphocytosis. Monoclonal integration of HTLV-I provirus DNA was detected, and a diagnosis of adult T-cell leukemia (ATL) was made. Flow cytometry revealed that the ATL cells expressed CD20 as well as T-cell-associated a
Adult T-cell leukemia
โ Scribed by T Uchiyama
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 990 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0268-960X
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Age and sex distributions of monoclonal gammopathy were studied for 12,196 healthy controls and 2056 patients with various malignancies. The frequency of monoclonal component in adult T-cell leukemia (ATL) patients was found to be much higher than that in patients with other malignancies and in heal
## Abstract Adult Tโcell leukemia/lymphoma (ATLL) patients are highly immunocompromised, but the underlying mechanism responsible for this state remains obscure. Recent studies demonstrated that __FOXP3__, which is a master control gene of naturally occurring regulatory T (Treg) cells, is expressed