𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Adrenergic Blocking Agents. V. Synthesis of N - Benzyl - N - (1 - phenoxyisopropyl) - β - chloroethylamine Hydrochloride Labeled with C 14

✍ Scribed by Nikawitz, Edward J.; Gump, William S.; Kerwin, James F.; Ullyot, Glenn E.

Book ID
126011846
Publisher
American Chemical Society
Year
1952
Tongue
English
Weight
238 KB
Volume
74
Category
Article
ISSN
0002-7863

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The preparation and purification of labe
The preparation and purification of labelled β-adrenergic blocking agents. Part I. Synthesis of carbon-14 and tritium labelled 1-isopropylamino-3-(1-naphthyloxy)-propan-2-ol hydrochloride, (propranolol hydrochloride, inderal
✍ J. Burns 📂 Article 📅 1970 🏛 John Wiley and Sons 🌐 French ⚖ 444 KB 👁 1 views

The preparation of 1"-propranolol hydrochloride from l-naphthol-I-14C is described. Several preparations of the compound have been carried out with overall radiochemical yields of 17 %-21 %. Specific activities of 3.51 pCilmg, 8.8 pCilmg, and 23.2 pCilmg have been obtained. Propranolol has also bee

Synthesis of [carbonyl-14C]- and (methox
Synthesis of [carbonyl-14C]- and (methoxy-d3)-labeled N-[(2RS, 3RS)-1-benzyl-2-methyl-3-pyrrolidinyl] −5-chloro-2-methoxy-4-(methylamino) benzamide (YM-09151-2). A new potent neuroleptic agent
✍ Kazuharu Tamazawa; Hideki Arima 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 French ⚖ 485 KB

## Abstract A new potent neuroleptic agent YM‐09151‐2, N‐[(2RS, 3RS)‐1‐benzyl‐2‐methyl‐3‐pyrrolidinyl]‐5‐chloro‐2‐methoxy‐4‐ (methylamino) benzamide (**10c**), was labeled with carbon‐14 and deuterium for biochemical studies such as metabolism and 14 pharmacokinetics. The synthesis of [carbonyl‐^14