Adrenal tumors inBRCA1/BRCA2 mutation carriers
β Scribed by Barak, Frieda ;Shiri-Svredlov, Ronit ;Bruchim-Bar Sade, Revital ;Kruglikova, Anna ;Friedman, Eitan ;Ben-Dor, David ;Goldberg, Iris
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 59 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Comparative genomic hybridization (CGH) analysis has shown that chromosome 5q deletions are the most frequent aberration in breast tumors from __BRCA1__ mutation carriers. To map the location of putative 5q tumor suppressor gene(s), 26 microsatellite markers covering chromosome 5 were u
The identification of cancer susceptibility genes offers new avenues for selecting high-risk individuals as subjects for chemoprevention trials. Because carriers of predisposing mutations are at high risk, they are more likely to enroll and comply with chemoprevention trials, and meaningful results