## Abstract Comparative genomic hybridization (CGH) analysis has shown that chromosome 5q deletions are the most frequent aberration in breast tumors from __BRCA1__ mutation carriers. To map the location of putative 5q tumor suppressor gene(s), 26 microsatellite markers covering chromosome 5 were u
Frequent somatic mutations ofGATA3in non-BRCA1/BRCA2familial breast tumors, but not inBRCA1-, BRCA2-or sporadic breast tumors
โ Scribed by Jeremy M. Arnold; David Y. H. Choong; Ella R. Thompson; kConFab; Nic Waddell; Geoffrey J. Lindeman; Jane E. Visvader; Ian G. Campbell; Georgia Chenevix-Trench
- Book ID
- 106378036
- Publisher
- Springer US
- Year
- 2009
- Tongue
- English
- Weight
- 179 KB
- Volume
- 119
- Category
- Article
- ISSN
- 0167-6806
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## Abstract ## BACKGROUND The prevalence of BRCA1 germline mutations is greater in the Ashkenazi Jewish population than in the general North American population. The Ontario Familial Breast Cancer Registry collects clinical and family history data in familial breast carcinoma cases, and unselected