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Adociasulfates 1, 7, and 8: New Bioactive Hexaprenoid Hydroquinones from the Marine Sponge Adocia sp.

โœ Scribed by Kalaitzis, John A.; de Almeida Leone, Priscila; Harris, Lisa; Butler, Mark S.; Ngo, Anna; Hooper, John N. A.; Quinn, Ronald J.

Book ID
127233339
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
67 KB
Volume
64
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Adociasulfates 1, 7
ChemInform Abstract: Adociasulfates 1, 7, and 8: New Bioactive Hexaprenoid Hydroquinones from the Marine Sponge Adocia sp.
โœ John A. Kalaitzis; Priscila de Almeida Leone; Lisa Harris; Mark S. Butler; Anna ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 29 KB

quinones from the Marine Sponge Adocia sp. -The structures of adociasulfates 1 (Ia), 7 (Ib), and 8 (II) are elucidated by 2D-NMR spectroscopy. Whereas bisulfate (Ia) inhibits proton pump activity in hen bone-derived membrane vesicles, monosulfate (Ib) possesses 10-fold decreased potency and adocias