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Adiponectin Protects Alveolar Type II Cells from Paraquat-induced Cytotoxicity via Attenuating Oxidative Stress

✍ Scribed by Y. Cao; Y. He; T. Yuan; R. Yao


Book ID
119295178
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
37 KB
Volume
43
Category
Article
ISSN
0736-4679

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## Abstract We evaluated the antioxidant role of peroxiredoxin 6 (Prdx6) in primary lung alveolar epithelial type II cells (AEC II) that were isolated from wild type (WT), Prdx6βˆ’/βˆ’, or Prdx6 transgenic (Tg) overexpressing mice and exposed to H~2~O~2~ at 50–500 Β΅M for 1–24 h. Expression of Prdx6 in