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Response of rat alveolar type II cells and human lung tumor cells towards oxidative stress induced by hydrogen peroxide and paraquat

✍ Scribed by Enrico Weidauer; Thomas Lehmann; Anja Rämisch; Elke Röhrdanz; Heidi Foth

Book ID
119377892
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
291 KB
Volume
151
Category
Article
ISSN
0378-4274

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## Abstract We evaluated the antioxidant role of peroxiredoxin 6 (Prdx6) in primary lung alveolar epithelial type II cells (AEC II) that were isolated from wild type (WT), Prdx6−/−, or Prdx6 transgenic (Tg) overexpressing mice and exposed to H~2~O~2~ at 50–500 µM for 1–24 h. Expression of Prdx6 in