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Adipocyte-released insulin-like growth factor-1 is regulated by glucose and fatty acids and controls breast cancer cell growth in vitro

✍ Scribed by V. D’Esposito, F. Passaretti, A. Hammarstedt, D. Liguoro, D. Terracciano…

Book ID: 120906284
Publisher: Springer
Year: 2012
Tongue: English
Weight: 430 KB
Volume: 55
Category: Article
ISSN: 0012-186X
DOI: 10.1007/s00125-012-2629-7

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## Abstract ## BACKGROUND Antagonists of growth hormone‐releasing hormone (GH‐RH) can inhibit the proliferation of various tumors either indirectly through the suppression of the pituitary growth hormone/hepatic insulin‐like growth factor I (__IGF‐I__) axis and the lowering of serum __IGF‐I__ conc