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ADF/cofilin-actin rods and synaptic loss in Alzheimer's disease

✍ Scribed by Bamburg, James R.; Bernstein, Barbara W.; Davis, Richard C.; Goldsbury, Claire; Maloney, Michael T.; Marsden, Ian T.; Minamide, Laurie S.; Pak, Chi W.; Perry, George; Podlisny, Marcia B.; Selkoe, Dennis J.; Shaw, Alisa E.; Siedlak, Sandra L.; Whiteman, Ineka T.

Book ID
123604027
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
48 KB
Volume
6
Category
Article
ISSN
1552-5260

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Immunofluorescence microscopy revealed that two actin-binding proteins of low molecular weight with different functional activity, ADF and cofilin, are transported into nuclei of cultured myogenic cells to form rod structures there together with actin, when the cells were incubated in medium contain