๐”– Bobbio Scriptorium
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Adenovirus Vectors as Transcomplementing Templates for the Production of Replication Defective Retroviral Vectors

โœ Scribed by W.Jay Ramsey; Natasha J. Caplen; Qin Li; James N. Higginbotham; Maulik Shah; R.Michael Blaese


Book ID
115582170
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
266 KB
Volume
246
Category
Article
ISSN
0006-291X

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## Abstract Herpes simplex virus type 1 (HSVโ€1) represents an attractive vehicle for a variety of gene therapy applications. To render this virus safe for clinical use, its cytotoxic genes must be removed without losing its ability to express transgenes efficiently. Our vectors are deleted for the