✦ LIBER ✦

Evaluation of Infection Parameters in the Production of Replication-Defective HSV-1 Viral Vectors

✍ Scribed by Ali Ozuer; James B. Wechuck; Brian Russell; Darren Wolfe; William F. Goins; Joseph C. Glorioso; Mohammad M. Ataai

Book ID: 109386398
Publisher: American Institute of Chemical Engineers
Year: 2002
Tongue: English
Weight: 255 KB
Volume: 18
Category: Article
ISSN: 8756-7938
DOI: 10.1021/bp010176k

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Engineering cell lines for production of

Engineering cell lines for production of replication defective HSV-1 gene therapy vectors

✍ Kyle G. Grant; David M. Krisky; Mohammed M. Ataai; Joseph C. Glorioso III 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 467 KB

## Abstract Herpes simplex virus type 1 (HSV‐1) represents an attractive vehicle for a variety of gene therapy applications. To render this virus safe for clinical use, its cytotoxic genes must be removed without losing its ability to express transgenes efficiently. Our vectors are deleted for the

Acute adrenal infection by HSV-1: role o

Acute adrenal infection by HSV-1: role of apoptosis in viral replication

✍ K. Aita; H. Irie; A. H. Koyama; A. Fukuda; T. Yoshida; J. Shiga 📂 Article 📅 2001 🏛 Springer Vienna 🌐 English ⚖ 625 KB

64 evaluation of a gene therapy system u

64 evaluation of a gene therapy system using a replication competent, non-neurovirulent HSV-1 viral vector used tn combination with radiotherapy

✍ Gregory S. Sibley; Dennis E. Hallahan; John Hyland; Lisa P. Seung; Helena J. Mau 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 104 KB

Gene transfer into enteric neurons of th

Gene transfer into enteric neurons of the rat small intestine in organ culture using a replication defective recombinant herpes simplex virus type 1 (HSV1) vector, but not recombinant adenovirus vectors

✍ Brown, O A; Santer, R M; Shering, A F; Larregina, A T; Morelli, A E; Southgate, 📂 Article 📅 1997 🏛 Nature Publishing Group 🌐 English ⚖ 966 KB

NK cells contribute to the early clearan

NK cells contribute to the early clearance of HSV-1 from the lung but cannot control replication in the central nervous system following intranasal infection

✍ Patrick C. Reading; Paul G. Whitney; Daniel P. Barr; Mark J. Smyth; Andrew G. Br 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 325 KB

Low levels of productive HIV infection i

Low levels of productive HIV infection in Langerhans cell-like dendritic cells differentiated in the presence of TGF-β1 and increased viral replication with CD40 ligand-induced maturation

✍ Tatsuyoshi Kawamura; Mehdi Qualbani; Elaine K. Thomas; Jan M. Orenstein; Andrew 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB 👁 2 views